Spring and fall are peak allergy seasons in many areas, with spring trees still pumping out millions of grains of pollen each day and the summer grasses already starting to contribute their share. Sneezing, running nose, and itching – itchy eyes, itchy nose, itchy throat – wouldn't it be great to be able to prevent allergies before they even got started.

Preventing asthma and allergies is possible, according to a study in the June 2003 issue of Thorax. Children at high risk for asthma and allergies were recruited in 1990 to be part of this study. Half of them went about life as normal, and the other half had a low-allergy diet as infants – starting with breast milk (with moms on a low-allergy diet) or Nutramigen formula (no milk or soy-based formula). This group of families also undertook significant measures to avoid exposure to house dust during infancy.

Avoiding inhaled allergens, though, may be another story. Other studies have shown that babies who are exposed to dogs and cats before the first birthday, for example, are far less likely to develop allergies later. It seems to me that the nose is designed to detect changes (which is why you often no longer notice even very strong odors if you are around them long enough). It seems to me that (or this, whichever) a baby’s nose learns what is "normal" to have around them in the air during the first year or so, and then begins to consider some later arrivals as dangerous invaders – the body develops an allergic response to them.

Allergies happen when the body is tricked into thinking that harmless particles are dangerous invaders. The immune system tries to get rid of these allergens by sneezing them out, flushing them out with tears or mucus, or dislodging them with nose rubbing. It tries to prevent them from getting into the lungs by constricting the airways. These are all normal responses to toxins and viruses. They are allergies if the trigger is not really a problem.

There may have been other differences between the two groups in the study. One half certainly worked harder and paid more attention to allergy issues. We still have a lot to learn. What’s exciting about this breakthrough study is that it demonstrates that preventing allergies, asthma, and eczema is truly possible. Now we just have to learn how best to do it.

1 Overview 2 Etiology 3 Symptoms 4 Treatment of symptoms

Overview Menopause occurs as the ovaries stop producing estrogen, causing the reproductive system to gradually shut down. As the body adapts to the changing levels of natural hormones, vasomotor symptoms such as hot flashes and palpitations, psychological symptoms such as increased depression, anxiety, irritability, mood swings and lack of concentration, and atrophic symptoms such as vaginal dryness and urgency of urination appear. Together with these symptoms, the woman may also have increasingly scanty and erratic menstrual periods. Technically, menopause refers to the cessation of menses; whereas the gradual process through which this occurs, which typically takes a year but may last as little as six months or more than five years, is known as climacteric. Popular use, however, replaces climacteric with menopause. A natural or physiological menopause is that (or this, whichever) which occurs as a part of a woman's normal aging process. However, menopause can be surgically induced by such procedures as hysterectomy (when this procedure includes oophorectomy, removal of the ovaries).

Etiology The cessation of menses is the result of the eventual atresia of almost all oocytes in the ovaries. This causes an increase in circulating FSH and LH levels as there are a decreased number of oocytes responding to these hormones and producing estrogen. This decrease in the production of estrogen leads to the post-menopausal symptoms of hot flashes, insomnia, osteoporosis, atherosclerosis, vaginal atrophy and depression. Cigarette smoking has been found to decrease the age at menopause by as much as one year however, premature menopause (before the age of 40) is generally idiopathic.

Treatment of symptoms Medical treatments for menopausal symptoms have been developed. Most notably, Hormone Replacement Therapy (HRT), has been used to reduce the weakening of bones (known as osteoporosis). However, some women have resisted the implication that menopause is a disorder, seeing it as a natural stage of life. There has also been scientific controversy over whether the benefits of HRT outweigh the risks. For many years, women were advised to take hormone therapy after menopause to reduce their risk of heart disease and various aspects of aging. However, a large, randomized, controlled trial (the Women's Health Initiative) found that women undergoing HRT had an increased risk of Alzheimer's disease, breast cancer, heart disease and stroke.